gnu: Add arriba.
* gnu/packages/bioinformatics.scm (arriba): New variable.
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@ -14445,3 +14445,69 @@ repeated areas between contigs.")
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"Velocyto is a library for the analysis of RNA velocity. Velocyto
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includes a command line tool and an analysis pipeline.")
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(license license:bsd-2)))
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(define-public arriba
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(package
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(name "arriba")
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(version "1.0.1")
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(source
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(origin
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(method url-fetch)
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(uri (string-append "https://github.com/suhrig/arriba/releases/"
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"download/v" version "/arriba_v" version ".tar.gz"))
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(sha256
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(base32
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"0jx9656ry766vb8z08m1c3im87b0c82qpnjby9wz4kcz8vn87dx2"))))
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(build-system gnu-build-system)
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(arguments
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`(#:tests? #f ; there are none
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#:phases
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(modify-phases %standard-phases
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(replace 'configure
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(lambda* (#:key inputs #:allow-other-keys)
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(let ((htslib (assoc-ref inputs "htslib")))
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(substitute* "Makefile"
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(("-I\\$\\(HTSLIB\\)/htslib")
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(string-append "-I" htslib "/include/htslib"))
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((" \\$\\(HTSLIB\\)/libhts.a")
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(string-append " " htslib "/lib/libhts.so"))))
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(substitute* "run_arriba.sh"
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(("^STAR ") (string-append (which "STAR") " "))
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(("samtools --version-only")
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(string-append (which "samtools") " --version-only"))
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(("samtools index")
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(string-append (which "samtools") " index"))
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(("samtools sort")
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(string-append (which "samtools") " sort")))
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#t))
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(replace 'install
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(lambda* (#:key outputs #:allow-other-keys)
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(let ((bin (string-append (assoc-ref outputs "out") "/bin")))
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(install-file "arriba" bin)
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(install-file "run_arriba.sh" bin)
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(install-file "draw_fusions.R" bin)
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(wrap-program (string-append bin "/draw_fusions.R")
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`("R_LIBS_SITE" ":" prefix (,(getenv "R_LIBS_SITE")))))
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#t)))))
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(inputs
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`(("htslib" ,htslib)
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("r-minimal" ,r-minimal)
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("r-circlize" ,r-circlize)
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("r-genomicalignments" ,r-genomicalignments)
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("r-genomicranges" ,r-genomicranges)
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("samtools" ,samtools)
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("star" ,star)
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("zlib" ,zlib)))
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(home-page "https://github.com/suhrig/arriba")
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(synopsis "Gene fusion detection from RNA-Seq data ")
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(description
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"Arriba is a command-line tool for the detection of gene fusions from
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RNA-Seq data. It was developed for the use in a clinical research setting.
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Therefore, short runtimes and high sensitivity were important design criteria.
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It is based on the fast STAR aligner and the post-alignment runtime is
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typically just around two minutes. In contrast to many other fusion detection
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tools which build on STAR, Arriba does not require to reduce the
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@code{alignIntronMax} parameter of STAR to detect small deletions.")
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;; All code is under the Expat license with the exception of
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;; "draw_fusions.R", which is under GPLv3.
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(license (list license:expat license:gpl3))))
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