diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 5e98aea91f..0a957139c9 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -6163,7 +6163,7 @@ SELECT or UPDATE queries to an end-point.")
 (define-public vsearch
   (package
     (name "vsearch")
-    (version "2.4.4")
+    (version "2.5.0")
     (source
      (origin
        (method url-fetch)
@@ -6173,7 +6173,7 @@ SELECT or UPDATE queries to an end-point.")
        (file-name (string-append name "-" version ".tar.gz"))
        (sha256
         (base32
-         "1d8a4gjwaqdv57krlr80x18mg5py1bbdiqs5m0jdn38filc9z40k"))
+         "1k8wf3qns4mqrsizywbkqcasqjw000m4drxsag3qd7390pwvf9kz"))
        (patches (search-patches "vsearch-unbundle-cityhash.patch"))
        (snippet
         '(begin