gnu: Add r-wavcluster.
* gnu/packages/bioconductor.scm (r-wavcluster): New variable.
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@ -5459,3 +5459,49 @@ with multiple R processes supported by the package @code{parallel}.")
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"This package provides methods for working with Illumina arrays using the
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@code{gdsfmt} package.")
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(license license:gpl3)))
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(define-public r-wavcluster
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(package
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(name "r-wavcluster")
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(version "2.18.0")
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(source
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(origin
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(method url-fetch)
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(uri (bioconductor-uri "wavClusteR" version))
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(sha256
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(base32
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"02i53dskirzr9nls3dsmv7dqhvy3vikkpx7247zpy2qd9r5yvhy2"))))
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(properties `((upstream-name . "wavClusteR")))
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(build-system r-build-system)
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(propagated-inputs
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`(("r-biocgenerics" ,r-biocgenerics)
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("r-biostrings" ,r-biostrings)
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("r-foreach" ,r-foreach)
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("r-genomicfeatures" ,r-genomicfeatures)
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("r-genomicranges" ,r-genomicranges)
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("r-ggplot2" ,r-ggplot2)
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("r-hmisc" ,r-hmisc)
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("r-iranges" ,r-iranges)
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("r-mclust" ,r-mclust)
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("r-rsamtools" ,r-rsamtools)
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("r-rtracklayer" ,r-rtracklayer)
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("r-s4vectors" ,r-s4vectors)
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("r-seqinr" ,r-seqinr)
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("r-stringr" ,r-stringr)
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("r-wmtsa" ,r-wmtsa)))
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(home-page "https://bioconductor.org/packages/wavClusteR/")
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(synopsis "Identification of RNA-protein interaction sites in PAR-CLIP data")
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(description
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"This package provides an integrated pipeline for the analysis of
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PAR-CLIP data. PAR-CLIP-induced transitions are first discriminated from
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sequencing errors, SNPs and additional non-experimental sources by a non-
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parametric mixture model. The protein binding sites (clusters) are then
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resolved at high resolution and cluster statistics are estimated using a
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rigorous Bayesian framework. Post-processing of the results, data export for
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UCSC genome browser visualization and motif search analysis are provided. In
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addition, the package allows to integrate RNA-Seq data to estimate the False
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Discovery Rate of cluster detection. Key functions support parallel multicore
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computing. While wavClusteR was designed for PAR-CLIP data analysis, it can
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be applied to the analysis of other NGS data obtained from experimental
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procedures that induce nucleotide substitutions (e.g. BisSeq).")
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(license license:gpl2)))
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