diff --git a/gnu/local.mk b/gnu/local.mk
index ea9c42449a..b1cf3c3de5 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -1025,7 +1025,6 @@ dist_patch_DATA =						\
   %D%/packages/patches/python-pandas-skip-failing-tests.patch	\
   %D%/packages/patches/python-paste-remove-website-test.patch	\
   %D%/packages/patches/python-paste-remove-timing-test.patch	\
-  %D%/packages/patches/python-pillow-freetype-2.7-test-failure.patch	\
   %D%/packages/patches/python-pygit2-disable-network-tests.patch	\
   %D%/packages/patches/python-pycrypto-CVE-2013-7459.patch	\
   %D%/packages/patches/python2-pygobject-2-gi-info-type-error-domain.patch \
diff --git a/gnu/packages/patches/python-pillow-freetype-2.7-test-failure.patch b/gnu/packages/patches/python-pillow-freetype-2.7-test-failure.patch
deleted file mode 100644
index 18bc30bc79..0000000000
--- a/gnu/packages/patches/python-pillow-freetype-2.7-test-failure.patch
+++ /dev/null
@@ -1,75 +0,0 @@
-Fix some test failures when building with freetype-2.7.
-
-https://github.com/python-pillow/Pillow/issues/2116
-https://github.com/python-pillow/Pillow/pull/2286
-
-Patch copied from upstream source repository:
-
-https://github.com/python-pillow/Pillow/commit/acf68c835c93ba144f83198306aa7e6082a43f43
-
-From acf68c835c93ba144f83198306aa7e6082a43f43 Mon Sep 17 00:00:00 2001
-From: hugovk <hugovk@users.noreply.github.com>
-Date: Mon, 12 Dec 2016 15:16:43 +0200
-Subject: [PATCH] Increase epsilon for FreeType 2.7
-
----
- Tests/test_imagefont.py | 15 ++++++++++-----
- 1 file changed, 10 insertions(+), 5 deletions(-)
-
-diff --git a/Tests/test_imagefont.py b/Tests/test_imagefont.py
-index de89ac92..5207dce3 100644
---- a/Tests/test_imagefont.py
-+++ b/Tests/test_imagefont.py
-@@ -125,7 +125,9 @@ try:
- 
-             target = 'Tests/images/rectangle_surrounding_text.png'
-             target_img = Image.open(target)
--            self.assert_image_similar(im, target_img, .5)
-+
-+            # Epsilon ~.5 fails with FreeType 2.7
-+            self.assert_image_similar(im, target_img, 2.5)
- 
-         def test_render_multiline(self):
-             im = Image.new(mode='RGB', size=(300, 100))
-@@ -144,7 +146,7 @@ try:
-             # some versions of freetype have different horizontal spacing.
-             # setting a tight epsilon, I'm showing the original test failure
-             # at epsilon = ~38.
--            self.assert_image_similar(im, target_img, .5)
-+            self.assert_image_similar(im, target_img, 6.2)
- 
-         def test_render_multiline_text(self):
-             ttf = ImageFont.truetype(FONT_PATH, FONT_SIZE)
-@@ -158,7 +160,8 @@ try:
-             target = 'Tests/images/multiline_text.png'
-             target_img = Image.open(target)
- 
--            self.assert_image_similar(im, target_img, .5)
-+            # Epsilon ~.5 fails with FreeType 2.7
-+            self.assert_image_similar(im, target_img, 6.2)
- 
-             # Test that text() can pass on additional arguments
-             # to multiline_text()
-@@ -178,7 +181,8 @@ try:
-                 target = 'Tests/images/multiline_text'+ext+'.png'
-                 target_img = Image.open(target)
- 
--                self.assert_image_similar(im, target_img, .5)
-+                # Epsilon ~.5 fails with FreeType 2.7
-+                self.assert_image_similar(im, target_img, 6.2)
- 
-         def test_unknown_align(self):
-             im = Image.new(mode='RGB', size=(300, 100))
-@@ -227,7 +231,8 @@ try:
-             target = 'Tests/images/multiline_text_spacing.png'
-             target_img = Image.open(target)
- 
--            self.assert_image_similar(im, target_img, .5)
-+            # Epsilon ~.5 fails with FreeType 2.7
-+            self.assert_image_similar(im, target_img, 6.2)
- 
-         def test_rotated_transposed_font(self):
-             img_grey = Image.new("L", (100, 100))
--- 
-2.12.0
-
diff --git a/gnu/packages/python.scm b/gnu/packages/python.scm
index d3bd2078b0..9fd7d9f6be 100644
--- a/gnu/packages/python.scm
+++ b/gnu/packages/python.scm
@@ -3686,15 +3686,14 @@ the OleFileIO module from PIL, the Python Image Library.")
 (define-public python-pillow
   (package
     (name "python-pillow")
-    (version "3.3.3")
+    (version "4.3.0")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "Pillow" version))
-       (patches (search-patches "python-pillow-freetype-2.7-test-failure.patch"))
        (sha256
         (base32
-         "0xkv0p1d73gz0a1qaasf0ai4262g8f334j07vd60bjrxs2wr3nmj"))))
+         "09xmn7rl6840sli2iz1k3fgxfgmri2nqz6vkinmb9mgg8ifp2z59"))))
     (build-system python-build-system)
     (native-inputs
      `(("python-nose"       ,python-nose)))
@@ -3706,6 +3705,8 @@ the OleFileIO module from PIL, the Python Image Library.")
        ("openjpeg" ,openjpeg)
        ("libtiff"  ,libtiff)
        ("libwebp"  ,libwebp)))
+    (propagated-inputs
+     `(("python-olefile" ,python-olefile)))
     (arguments
      `(#:phases (modify-phases %standard-phases
                   (add-after