gnu: Add r-rcistarget.

* gnu/packages/bioconductor.scm (r-rcistarget): New variable.
master
Ricardo Wurmus 2019-08-15 17:39:11 +02:00
parent 19f1aac0e7
commit bb88417fb7
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@ -5089,6 +5089,41 @@ by a sparse number of variables, this method can reduce the complexity of
data, to only emphasize the data that actually matters.") data, to only emphasize the data that actually matters.")
(license license:expat))) (license license:expat)))
(define-public r-rcistarget
(package
(name "r-rcistarget")
(version "1.4.0")
(source
(origin
(method url-fetch)
(uri (bioconductor-uri "RcisTarget" version))
(sha256
(base32
"133x2vr86ifbk82q08x1c8q19zsk5za7b6qrzz77dhsyf4bhcvpd"))))
(properties `((upstream-name . "RcisTarget")))
(build-system r-build-system)
(propagated-inputs
`(("r-aucell" ,r-aucell)
("r-biocgenerics" ,r-biocgenerics)
("r-data-table" ,r-data-table)
("r-feather" ,r-feather)
("r-gseabase" ,r-gseabase)
("r-r-utils" ,r-r-utils)
("r-summarizedexperiment" ,r-summarizedexperiment)))
(home-page "https://aertslab.org/#scenic")
(synopsis "Identify transcription factor binding motifs enriched on a gene list")
(description
"RcisTarget identifies @dfn{transcription factor binding motifs} (TFBS)
over-represented on a gene list. In a first step, RcisTarget selects DNA
motifs that are significantly over-represented in the surroundings of the
@dfn{transcription start site} (TSS) of the genes in the gene-set. This is
achieved by using a database that contains genome-wide cross-species rankings
for each motif. The motifs that are then annotated to TFs and those that have
a high @dfn{Normalized Enrichment Score} (NES) are retained. Finally, for
each motif and gene-set, RcisTarget predicts the candidate target genes (i.e.
genes in the gene-set that are ranked above the leading edge).")
(license license:gpl3)))
(define-public r-cicero (define-public r-cicero
(package (package
(name "r-cicero") (name "r-cicero")