diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 77a902ef4e..30ac8a80e9 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -7505,7 +7505,7 @@ downloaded from Encode.")
 (define-public r-org-hs-eg-db
   (package
     (name "r-org-hs-eg-db")
-    (version "3.4.0")
+    (version "3.5.0")
     (source (origin
               (method url-fetch)
               ;; We cannot use bioconductor-uri here because this tarball is
@@ -7515,7 +7515,7 @@ downloaded from Encode.")
                                   "org.Hs.eg.db_" version ".tar.gz"))
               (sha256
                (base32
-                "19mg64pw8zcvb9yxzzyf7caz1kvdrkfsj1hd84bzq7crrh8kc4y6"))))
+                "1v6wa5613cjq59xd7x1qz8lr9nb2abm9abl2cci1khrnrlpla927"))))
     (properties
      `((upstream-name . "org.Hs.eg.db")))
     (build-system r-build-system)