diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 5815c391cf..5a1da25805 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -8511,14 +8511,14 @@ library implementing most of the pipeline's features.")
 (define-public r-mutationalpatterns
   (package
     (name "r-mutationalpatterns")
-    (version "1.4.2")
+    (version "1.4.3")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "MutationalPatterns" version))
        (sha256
         (base32
-         "08ay9h5cqsi8ypb6r0g4rfa5l1g06jgfzl64wmhgz134yqbl7vfv"))))
+         "0ml4gsp5dfv23xqrknxh25q8q65hly1xb1215lcwyc8hj9z8f941"))))
     (build-system r-build-system)
     (propagated-inputs
      `(("r-biocgenerics" ,r-biocgenerics)
@@ -8528,7 +8528,6 @@ library implementing most of the pipeline's features.")
        ("r-genomicranges" ,r-genomicranges)
        ("r-genomeinfodb" ,r-genomeinfodb)
        ("r-ggplot2" ,r-ggplot2)
-       ("r-gridextra" ,r-gridextra)
        ("r-iranges" ,r-iranges)
        ("r-nmf" ,r-nmf)
        ("r-plyr" ,r-plyr)