On Guix, Python modules are in a different output from the executables, so searching "../share/glib-2.0" will not work. This patch restores behaviour prior to this commit: --- a/gio/gdbus-2.0/codegen/gdbus-codegen.in +++ b/gio/gdbus-2.0/codegen/gdbus-codegen.in @@ -25,9 +25,12 @@ srcdir = os.getenv('UNINSTALLED_GLIB_SRCDIR', None) filedir = os.path.dirname(__file__) +datadir = os.path.join('@datadir@', 'glib-2.0') if srcdir is not None: path = os.path.join(srcdir, 'gio', 'gdbus-2.0') +elif os.path.exists(os.path.join(datadir, 'codegen')): + path = datadir elif os.path.basename(filedir) == 'bin': # Make the prefix containing gdbus-codegen 'relocatable' at runtime by # adding /some/prefix/bin/../share/glib-2.0 to the python path